S2 ABOestimator

screenshot

S2 ABOestimator by SilvaSquare is a program to estimate the allele frequencies of the ABO blood group system, and perform a couple of statistical tests on the data. It requires M$ Windows (95+) or a good emulator.

It is very simple to use, and is meant to be used in teaching, particularly

  1. to compare simple heuristic estimates of the allele frequencies
  2. to show the EM algorithm in action, to obtain maximum likelihood (ML) estimates of the allele frequencies
  3. to perform goodness-of-fit tests of the Hardy-Weinberg assumption.

Some example data sets are provided to get you started. You can also use your own data (or make them up, and experiment). Rather extensive help is provided, both scientific and on using the program.

Comments (pan or praise) are welcome!

The program is NOT meant to be used in clinical applications, or any life-threatning situations. It is offered "as is", with no warranties whatsoever.

It is postcardware (meaning, if you like it, you should send me a nice postcard from your home town, but you should never have to pay for it, or ask anyone to pay you for it), and normally resides in http://webpages.fc.ul.pt/~pjns/Soft/ABOestimator/.

It does not require setup, makes no changes to the windows registry, is really simple to install (just unzip the files into a directory of your choice).

If you use the program more than a couple times, please consider Should you use it in work leading to a publication, please cite the program and the above web site.

S2 ABOestimator is Copyright Pedro J.N. Silva, 2000-2002. SilvaSquare is a trademark of Pedro J.N. Silva.

download S2 ABOestimator now (zipped)

Have much fun!

Pedro J.N. Silva
Faculdade de Ciencias da Universidade de Lisboa
Campo Grande, C2, 4o. piso
P-1700 LISBOA PORTUGAL